Publications

We have published

Our founders have published work in fields varying from Epigenetics and Systems Biology to Clinical Nutrition and Maternal Health. You can find a complete list of publications here.

Diabetes
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Systems Biology
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Epigenetics
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Clinical Nutrition
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S.No.PublicationsCategories
1Vionnet N, Stoffel N, Takeda K, Bell GI, Zouali H, Lesage S, Velho G, Passa PH, Iris F, Froguel P, and Cohen D. (1992) Nonsense mutation in the glucokinase gene causes early onset non-insulin dependent diabetes mellitus. Nature, 356:721-722. (4*)DIABETES
 Abderrahim H, Sambucy J L , Iris F, Ougen P, Billault A, Chumakov I M , Dausset J, Cohen D, Le Paslier D: Cloning the human major histocompatibility complex in YACs. Genomics. 1994;23(3):520-7. doi: 10.1006/geno.1994.1538.GENETICS
2Iris F, Bougueleret L, Prieur S, Rodriguez-Tome P, Caterina, D, Perrot V, Primas G, Dausset J and Cohen D.(1993) Dense Alu clustering and a potential new member of the NF kappa B family within a 90 kilobase HLA class III segment. Nature Genet. 3:137-145. (5*)GENETICS
3Glücksmann-Kuis MA, Iris F, Tyber O, Woolf EA, Bougueleret L, Deng N, Alperin GD, Hawkins F, Munro C, Lakey N, Duyk G, Schneider MC, Geng L, Zhang F, Zhao Z. et al (1995) Polycystic Kidney Disease: the complete structure of the PKD1 gene and its protein. Cell 81:289-298.GENETICS
 Gimeno R.E, Dembski M, Weng X, Deng N, Shyjan A.W , Gimeno C.J , Iris F, Ellis C.J , Woolf E.A, Tartaglia L.A: Cloning and characterization of an uncoupling protein homolog: a potential molecular mediator of human thermogenesis. Diabetes. 1997; 46(5):900-6. doi: 10.2337/diab.46.5.900.GENETICS
4Gadal F, Bozic C, Pillot-Brochet C, Malinge S, Wagner S, Le Cam A, Buffat L, Crepin M and Iris F. (2003) Integrated transcriptome analysis of the cellular mechanisms associated with Ha-ras dependent malignant transformation of the human breast epithelial MCF-7 cell-line. NAR. 39:5789-5804.SYSTEMS BIOLOGY
5Gadal F, Bozic C, Pillot-Brochet C, Malinge S, Wagner S, Le Cam A, Vicenzi J, Buffat L, Perret G, Iris F and Crepin M. (2005) Integrative analysis of gene expression patterns predicts specific modulations of defined cell functions by estrogen and tamoxifen in MCF7 cells. JMol.Endocrinol.34:61-75.SYSTEMS BIOLOGY
6Iris F, Gea M, Lampe PH and Santamaria P.(2009) Production and implementation of predictive biological models. Med Sci. 25: 608-16.SYSTEMS BIOLOGY
7Pouillot F, Blois H & Iris F (2010) Genetically engineered virulent phage banks in the detection and control of emergent pathogenic bacteria. Biosecur Bioterror. 8:155-69.SYSTEMS BIOLOGY
8Iris F, Filiou M & Türck C.W (2014): Differential Proteomics Analyses Reveal Anxiety-Associated Molecular and Cellular Mechanisms in Cingulate Cortex Synapses. Am. J. Psychiatry Neurosci. 2:25-42SYSTEMS BIOLOGY
9Iris F, Scott RS and Mann JI: Genetic factors in Diabetes Mellitus. In “Clinical Diabetes Mellitus, a problem-oriented approach.” 2d edition. JK Davidson, Ed., pp 58-67, Thieme Medical Publishers Inc. New York,1991.DIABETES
10Iris F: Optimised methods for large scale shot-gun DNA sequencing in Alu-rich genomic regions. In “Automated DNA sequencing and analysis.” M.D Adams, C Field and J.C. Venter Eds., pp 199-209, Academic Press Ltd, 1993.GENETICS
11Gadal F, Bozic C, Pillot-Brochet C, Malinge S, Wagner S, Le Cam A, Vicenzi J, Buffat L, Perret G, Iris F and Crepin M. Identification and computer-assisted integration into biological pathways of modulated gene expressions patterns. In “Bioinformatics: New Research”, Volume 1. Yan P.V Ed., pp 81-100. Nova Science Publishers, New York, 2005.SYSTEMS BIOLOGY
12Iris F: Biological modelling in the discovery and validation of cognitive dysfunctions biomarkers. In “Biomarkers for psychiatric disorders”. C.W. Turck Ed., pp 473-522. Springer, New York, 2008.SYSTEMS BIOLOGY
13Türck CW and Iris F. Proteome-Based Pathway Modelling of Psychiatric Disorders. Pharmacopsychiatry. 2011; 44 Suppl 1:S54-61.SYSTEMS BIOLOGY
14Iris F: Psychiatric Systems Medicine: Closer at Hand than Anticipated but not with the Expected Portrait. Pharmacopsychiatry. 2012; 45 Suppl 1:S12-21.SYSTEMS BIOLOGY
15Iris F, Gea M, Lampe P-H, and Querleux B: Heuristic Modeling Applied to Epidermal Homeostasis. In “Computational Biophysics of the Skin”. B. Querleux Ed., pp.461-524. Jenny Stanford Publishing, 2014.SYSTEMS BIOLOGY
16Pandit P, Galande S, Iris F. Maternal malnutrition and anaemia in India: dysregulations leading to the ‘thin-fat’ phenotype in newborns. J Nutr Sci. 2021;10:e91. Published 2021 Oct 11. doi:10.1017/jns.2021.83SYSTEMS BIOLOGY
 Iris F, Beopoulos A, Gea M:How scientific literature analysis yields innovative therapeutic hypothesis through integrative iterations.Curr Opin Pharmacol. 2018; 42:62-70. DOI: 10.1016/j.coph.2018.07.005SYSTEMS BIOLOGY
 Bessiere B, Iris F, Milet A, Beopoulos A, Billoet C, Farjot G: A new mechanistic approach for the treatment of chronic neuropathic pain with nitrous oxide integrated from a systems biology narrative review. Med Gas Res. 2021; 11(1):34-41. doi: 10.4103/2045-9912.310058.SYSTEMS BIOLOGY
 Beopoulos A, Gea M, Fasano A, Iris F: Autonomic Nervous System Neuroanatomical Alterations Could Provoke and Maintain Gastrointestinal Dysbiosis in Autism Spectrum Disorder (ASD): A Novel Microbiome-Host Interaction Mechanistic Hypothesis. Nutrients. 2021; 14(1):65. doi: 10.3390/nu14010065.SYSTEMS BIOLOGY
17Bhat DS, L Gruca, Bennet C, Katre P, Kurpad A, Yajnik CS, Kalhan SC. Evaluation of tracer labelled methionine load test in vitamin B-12 deficient adolescent women. PLOS ONE, 2018. women. PLoS ONE 13(5):e0196970.CLINICAL NUTRITION
18Katre P, Joshi S, Bhat D, Deshmukh M, Gurav N, Pandit S, Lubree H, Marczewski S, Bennett C, Yajnik CS, Kalhan SC. Effect of multinutrient insufficiency on markers of one carbon metabolism in young women: response to a methionine load. Eur. J. Clin. Nutr, 2015 Sep 16. doi: 10.1038/ejcn.2015.155. [Epub ahead of print].CLINICAL NUTRITION
19Yajnik CS, Katre P, Joshi S M, Kumaran K, Bhat DS, Lubree H, Memane N, Kinare A, Pandit A, Bhave S, Bavdekar A and Fall CH. Fall. Higher glucose, insulin and insulin resistance (HOMA-IR) in childhood predict adverse cardiovascular risk in early adulthood: the Pune Children’s Study. Diabetologia. 2015; 58: 1626–1636.DIABETES
20Yajnik CS, Chandak GR, Joglekar C, Katre P, Bhat DS, Singh SN, Janipalli CS, Refsum H, Ghattu K, Veena S, Osmond C, Fall CH. Maternal homocysteine in pregnancy and offspring birthweight: epidemiological associations and Mendelian randomization analysis Int. J. Epidemiol. 2014, 43: 1487-1497.CLINICAL NUTRITION
21Joshi S, Katre P, Kumaran K, Joglekar C, Osmond C, Bhat DS, Lubree H, Pandit A, Yajnik CS, Fall CH. Tracking of cardiovascular risk factors from childhood to young adulthood – the Pune Children’s Study. Int J Cardiol. 2014, 175:176-178.CLINICAL NUTRITION
22Rush EC, Katre P, Yajnik CS. Vitamin B12: one carbon metabolism, fetal growth and programming for chronic disease. Eur J Clin Nutr. 2014, 68: 2-7.CLINICAL NUTRITION
23Deshmukh U, Katre P, Yajnik CS. Influence of maternal vitamin B12 and folate on growth and insulin resistance in the offspring. Nestle Nutr Inst Workshop Ser. 2013; 74:145-156.MATERNAL AND CHILD HEALTH
24Lubree H, Katre P, Joshi S, Bhat DS, Deshmukh U, Memamne N, Otive S, Rush E, Yajnik CS. Child’s homocysteine concentration at 2 years is influenced by pregnancy vitamin B12 and folate status. J Dev Orig Health Dis. 2012, 3: 32–38.MATERNAL AND CHILD HEALTH
25Hardikar P, Joshi S, Bhat DS, Raut D, Katre P, Lubree HG, Jere A, Pandit A, Fall CH, Yajnik CS. Spuriously High Prevalence of Prediabetes Diagnosed by HbA1c in Young Indians Partly Explained by Hematological Factors and Iron Deficiency Anemia. Diabetes Care. 2012, 35:797-802.DIABETES
26Bhate V, Joshi S, Ladkat R, Deshmukh U, Lubree H, Katre P, Bhat D, Rush E, Yajnik CS. Vitamin B12 and folate during pregnancy and offspring motor, mental and social development at 2 years of age. J Dev Orig Health Dis. 2012, 3: 123–130.MATERNAL AND CHILD HEALTH
27Naik S, Joglekar C, Bhat D, Lubree H, Rege S, Raut K, Katre P, Rush E, Yajnik C. Marked Gender Difference in Plasma Total Homocysteine Concentrations in Indian Adults with low Vitamin B12. Int J Vitam Nutr Res. 2011; 81:306-316.CLINICAL NUTRITION
28Katre P, Bhat D, Lubree H, Otiv S, Joshi S, Joglekar C, Rush E, Yajnik C. Vitamin B12 and folic acid supplementation and plasma total homocysteine concentrations in pregnant Indian women with low B12 and high folate status. Asia Pac J Clin Nutr 2010;(19): 335-343.MATERNAL AND CHILD HEALTH
29Khare S, Katre P, and Galande S. Epigenetic Regulation of Islet Development and Regeneration. In ‘Pancreatic Islet Biology’, Editor: Anandwardhan Hardikar, To be published in Nov, 2016 by Springer.EPIGENETICS
30Katre P and Yajnik CS (2015). Influence of Early Life Environment on Risk of Non-Communicable Diseases (NCDs) in Indians: Pune Experience. Sight and Life, 2015, VOL 29(1)MATERNAL AND CHILD HEALTH
31Yajnik CS, Deshmukh U, Katre P. (2016). Vitamin B12 Deficiency in Developing and Newly Industrialising Countries For the book titled: Vitamin B12: advances and insights (Accepted for Publication). Science Publishers. Editor Dr Rima Obeid, Aarhus University, Denmark.CLINICAL NUTRITION
32Khare SP, Shetty A, Biradar R, Patta I, Sathe A, Reddy PC, Chen Z, Lahesmaa R and Galande S*. (2019) NF-kB signaling and IL-4 signaling regulate SATB1 expression via alternative promoter usage during Th2 differentiation. Frontiers in Immunology 2019 Apr 2;10:667. doi: 10.3389/fimmu.2019.00667. eCollection 2019.EPIGENETICS
33Tripathi ST*, Välikangas T*, Shetty A*, Khan MM, Bhosale SD, Moulder R, Komsi E, Salo V, Albuquerque RSD, Rasool O, Galande S, Elo LE#, and Lahesmaa R#. (2019) Quantitative mass spectrometry-based proteomics reveals the dynamic protein landscape during initiation of human Th17 cell polarization. iScience;11:334-355. doi: 10.1016/j.isci.2018.12.020. Epub 2018 Dec 26.EPIGENETICS
34Naik R and Galande S#. (2018) SATB family chromatin organizers as master regulators of tumor progression. Oncogene 38:1989-2004.GENETICS
35Mir R, Sharma A, Pradhan SJ, Galande S#. (2018) Regulation of transcription factor SP1 by β-catenin destruction complex modulates Wnt response. Mol Cell Biol 38:pii: e00188-18. doi: 10.1128/MCB.00188-18. Print 2018 Nov 15.EPIGENETICS
36Muralidharan B, Keruzore M, Pradhan S, Roy B, Shetty A, Kinare A, D’souza L, Maheshwari U, Karmodiya K, Suresh A, Galande S, Bellefroid E, and Tole S. (2017) Dmrt5, a novel neurogenic factor, reciprocally regulates Lhx2 to control the neuron-glia cell fate switch in the developing hippocampus. J Neurosci. 37:11245-11254.EPIGENETICS
37Muralidharan B, Khatri Z, Maheshwari U, Gupta R, Roy B, Pradhan S, Karmodiya K, Padmanabhan H, Shetty A, Balaji C, Kolthur-Seetharam U, Macklis J, Galande S, and Tole S. (2017) Lhx2 interacts with the NuRD complex and regulates cortical neuron subtype determinants Fezf2 and Sox11. J Neurosci. 37:194-203.EPIGENETICS
38Gottimukkala KP, Jangid R, Patta I, Sultana DA, Sharma A, Misra-Sen J, and Galande S#. (2016) Regulation of SATB1 during thymocyte development by TCR signaling. Mol. Immunol. 2016 Jul 22;77:34-43.EPIGENETICS
39Pusalkar M, Ghosh S, Jaggar M, Husain BF, Galande S, Vaidya VA. (2016) Acute and Chronic Electroconvulsive Seizures (ECS) Differentially Regulate the Expression of Epigenetic Machinery in the Adult Rat Hippocampus. 2016; Int J Neuropsychopharmacol. 2016 May 17. pii: pyw040. doi: 10.1093/ijnp/pyw040. [Epub ahead of print].EPIGENETICS
40Reddy PC, Sinha I, Kelkar A, Habib F, Pradhan SJ, Sukumar R, and Galande S#. (2015) Comparative sequence analyses of genome and transcriptome reveal novel transcripts and variants in the Asian elephant Elephas maximus. J Biosci. 40:891-907.EPIGENETICS
41Pusalkar M, Suri D, Kelkar A, Bhattacharya A, Galande S, and Vaidya VA. (2015) Early stress evokes dysregulation of histone modifiers in the medial prefrontal cortex across the life span. Dev. Psychobiol. 58:198-210.EPIGENETICS
42Karmodiya K#, Pradhan SJ, Joshi B, Jangid R, Reddy PC, Galande S. (2015) A comprehensive epigenome map of Plasmodium falciparum reveals unique mechanisms of transcriptional regulation and identifies H3K36me2 as a global mark of gene suppression. Epigenetics Chromatin. 2015 Sep 17;8:32. doi: 10.1186/s13072-015-0029-1. eCollection 2015.EPIGENETICS
43Hardikar AA#, Satoor SN, Karandikar MS, Joglekar MV, Puranik AS, Wong W, Kumar S, Limaye A, Bhat DS, Januszewski A, Umrani MR, Ranjan AK, Apte K, Yajnik P, Bhonde RR, Galande S, Keech AC, Jenkins AJ, and Yajnik CS. (2015) Susceptibility to obesity and diabetes following multigeneration undernutrition is not reversed by two generations of nutrient availability. Cell Metab. 22:312-319.CLINICAL NUTRITION
44Mir R, Pradhan SJ, Patil P, Mulherkar R and Galande S#. (2015) Wnt/β-catenin signaling regulated SATB1 promotes colorectal cancer tumorigenesis and progression. Oncogene. 35:1679-1691.GENETICS
45Karmodiya K#, Krishanpal A, Muley V, Pradhan SJ, Bhide Y, and Galande S. (2014) Camello, a novel family of Histone Acetyltransferases that acetylate histone H4 and is essential for zebrafish development. Sci Rep. 4:6076. doi: 10.1038/srep06076.EPIGENETICS
46Suri D, Veenit V, Sarkar A, Thiagarajan D, Kumar A, Nestler EJ, Galande S, Vaidya VA. (2012) Early Stress Evokes Age-Dependent Biphasic Changes in Hippocampal Neurogenesis, Bdnf Expression, and Cognition. Biol Psychiatry. 73:658-666.EPIGENETICS
47Mir R, Pradhan SJ, Galande S#. (2012) Chromatin organizer SATB1 as a novel molecular target for cancer therapy. Curr Drug Targets. 13:1603-1615.GENETICS
48Burute M, Gottimukkala KP, Galande S#. (2012) Chromatin organizer SATB1 is an important determinant of T cell differentiation. Immunol. Cell Biol. 90:852-859.EPIGENETICS
49Khare SP, Habib F, Sharma R, Gadewal N, Gupta S#, Galande S#. (2012) HIstome–a relational knowledgebase of human histone proteins and histone modifying enzymes. Nucleic Acids Res. 40(Database issue):D337-342.GENETICS
50Khare S, Katre P, and Galande S#. Epigenetic Regulation of islet development and regeneration, In ‘Pancreatic Islet Biology’ Edited by: Dr. Anandwardhan Hardikar, Published by Springer, 2016.EPIGENETICS
 *Equal contribution #Corresponding author